Chelsea’s hypotension drug fails to prove efficacy past week one

(Reuters) – Chelsea Therapeutics Inc said its experimental hypotension drug met the main goal of a study by significantly reducing dizziness in patients at week one, but results beyond that period were not statistically significant.The U.S. Food and Drug Administration declined to approve the drug, Northera, in March, and asked for data that proved it was effective over two to three months.The company’s...

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Obama firm on “fiscal cliff” amid Republican disarray

WASHINGTON (Reuters) – President Barack Obama held his ground on the “fiscal cliff” on Tuesday, insisting on higher tax rates for the wealthiest Americans, while Republicans showed increasing disarray over how far they should go to compromise with Obama‘s demands.With less than a month left to confront the budget cuts and tax increases that will begin taking effect in January unless Congress acts,...

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‘The Daily’ doomed by dull content and isolation

LOS ANGELES (AP) — It was too expensive. It lacked editorial focus. And for a digital publication, it was strangely cut off from the Internet. That’s the obituary being written in real time through posts, tweets and online chats about The Daily, the first-of-its-kind iPad newspaper that is being shut down this month.Rupert Murdoch‘s News Corp. said Monday that The Daily will publish its final issue...

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U.S. court voids drug rep’s conviction, cites free speech

NEW YORK (Reuters) – A divided federal appeals court on Monday threw out the conviction of a sales representative for promoting off-label use of a prescription drug, a ruling that could make it harder for the government to police how drugs are marketed and sold.The 2nd U.S. Circuit Court of Appeals in New York found that the sales representative’s free speech rights under the First Amendment had been...

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Wall Street sours on weak domestic factory data

NEW YORK (Reuters) – Stocks struggled to extend the previous week’s gains, dropping on Monday as disappointing U.S. factory numbers dampened optimism about China‘s economic growth.The declines broke a three-day streak of gains for the S&P 500, keeping it shy of its 50-day moving average of about 1,420, a level that the index has been below since October 22, and now serving as a key resistance...

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Official: Syria moving chemical weapons components

WASHINGTON (AP) — U.S. and allied intelligence have detected Syrian movement of chemical weapons components in recent days, a senior U.S. defense official said Monday, as the Obama administration strongly warned the Assad regime against using them.A senior defense official said intelligence officials have detected activity around more than one of Syria‘s chemical weapons sites in the last week. The...

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Nintendo president apologizes for bulky day-one Wii U firmware update

As we noted in our first impressions, Nintendo’s (NTDOY) Wii U is charting new ground with its wireless GamePad and touchscreen controls that engage gamers in the living room like never before. But before you can even set up the Wii U, a mandatory firmware update is required upon power up. Gamers everywhere were frustrated to learn that the firmware update, which is pegged anywhere...

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Clinton in Prague to lobby for Westinghouse nuclear bid

PRAGUE (Reuters) – U.S. Secretary of State Hillary Clinton will seek to convince Czech leaders of the advantages of picking U.S. firm Westinghouse over a Russian rival as the contractor for a $ 10 billion nuclear reactor project in meetings in Prague on Monday.U.S. officials traveling with Clinton to Prague said the Temelin nuclear power project could bring as many as 9,000 jobs to the United States...

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News International chief to leave

2 December 2012 Last updated at 21:18 ETNews International chief executive Tom Mockridge is to leave his role at the end of December.Mr Mockridge, who replaced Rebekah Brooks in July 2011, is stepping down to “pursue outside opportunities”, News Corporation announced.Rupert Murdoch, chairman and chief executive of News Corp, said Mr Mockridge’s decision was “absolutely and entirely his own”.News International...

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Egypt’s anti-Morsi rebellion of judges is complete

CAIRO (AP) — Egypt‘s rebellion of the judges against President Mohammed Morsi became complete on Sunday with the country’s highest court declaring an open-ended strike on the day it was supposed to rule on the legitimacy of two key assemblies controlled by allies of the Islamist leader.The strike by the Supreme Constitutional Court and opposition plans to march on the presidential palace on Tuesday...

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