Beyonce to direct documentary about herself for HBO












LOS ANGELES (Reuters) – Pop superstar Beyonce is stepping behind the camera to direct a behind-the-scenes documentary about her personal and professional life, U.S. cable channel HBO said on Monday.


The currently untitled film will debut on February 16 and show the Grammy-winning singer’s life in the recording studio, readying for live performances and running her own TV and music production company.












“Everybody knows Beyonce’s music, but few know Beyonce the person,” HBO Programming President Michael Lombardo said in a statement. “Along with electrifying footage of Beyonce on stage, this unique special looks beyond the glamour to reveal a vibrant, vulnerable, unforgettable woman.”


The documentary will also feature moments in the “Crazy in Love” singer’s family life and first-person footage Beyonce captured on her laptop.


Beyonce, 31, who is married to hip hop artist and mogul Jay-Z, will headline the Super Bowl halftime show in New Orleans on February 3.


(Reporting By Eric Kelsey, editing by Jill Serjeant and Andrew Hay)


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HIV Vaccine Under Study May Last A Lifetime












A genetically-engineered HIV vaccine under study by Texas researchers works in a novel way.


It targets specific cells exactly where the virus enters the body, stimulating them to generate an immune response so the virus can’t take hold.












If the strategy bears out, the vaccine will be a single dose and last a lifetime, says Marie-Claire Gauduin, PhD, assistant scientist at Texas Biomedical Research Institute.


”Many other HIV vaccines try to block the infection when the virus is already in,” she says.  ”Here we try not to be infected to begin with,” Gauduin tells Take Part.


RELATED: Breakthrough: Early HIV Treatment Virtually Erases Risk of Passing Virus On


About 33 million people worldwide are living with  HIV/AIDS, according to estimates by the Joint United Nations Programme on HIV/AIDS.  Most do not know it. The new vaccine, if perfected, could be given to children at puberty to stem this toll, Gauduin says.


Most new cases of HIV infections worldwide are transmitted by sexual intercourse through outer layers of cells known as epithelial cells. These line the surfaces of structures throughout the body.


The target of the new vaccine is the mucosal layers of the epithelium in the genital and rectal areas, where the virus  typically enters.


“We are targeting the basal layer, the lower layer of epithelial stem cells,” she says. These stem cells divide and differentiate into specialized cell types.


The vaccine stays put in the epithelial stem cells, she says. Next, antigens that recognize the virus are produced.  ”These antigens stimulate your immune response to fight the virus,” she says.


“The virus will be recognized at the site of entry,” she says. “The virus won’t get to the blood stream is the hope.”


What makes it long lasting, she says, is the initial targeting of the stem cells. “Once the epithelial stem cell gets the message to stimulate your immune response, it will do so constantly,” she says, so the virus will be recognized long term.


Gauduin and her colleagues recently filed for a patent on the approach.


The vaccine, of course, is years from clinical practice, she says. “We have a lot of work to do,” she tells Take Part. Primate studies may start in early 2013. Human trials may begin as early as 2015.


Currently, other HIV vaccine approaches can’t deliver the antibody production for long periods of time. So the protection is weak and temporary, Gauduin says.


“It looks very interesting, certainly a great idea,” say Yegor Voronin, PhD, science officer for Global HIV Vaccine Enterprise, an alliance devoted to developing a preventive HIV vaccine.


RELATED: FDA Approves Truvada as First HIV Prevention Drug


The approach makes sense to scientists like him. “Epithelial cells don’t live very long,” he says. “They are continuously shed off. They are trying to affect the stem cells that produce epithelial cells. As the stem cells differentiate into epithelial cells, that is when they start producing the antigen.”


“It’s very early stages,” he says. “It’s an excellent idea. Whether it will work–who knows?”


Many other attempts have not panned out, he says.


One important as-yet unanswered question, he says, is whether the vaccine could cause some sort of health problem ”and you have the antigen being expressed continuously.” He asks: “How are you going to turn that off?”


Much safety testing, among other research, will be needed, he says.


As with other vaccines under development, he says a wait-and-see stance is best. “At this point, it’s just way too early to tell.”



Kathleen Doheny is a Los Angeles journalist who writes about health. She doesn’t believe inmiracle cures, but continues to hope someone will discover a way for joggers to maintain their pace.


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Eurozone deal on Greece bailout















Olli Rehn: “Greece has kept its commitments”



Eurozone finance ministers and the IMF have reached a deal on an urgently needed bailout for debt-laden Greece.


They have agreed to cut debts by 40bn euros ($ 51bn; £32bn) and have paved the way for releasing the next tranche of bailout loans – some 44bn euros.


Greek Prime Minister Antonis Samaras welcomed the deal, saying “a new day begins for all Greeks”.


Asian shares climbed on news of the agreement.


MSCI’s broadest index of Asia Pacific shares outside Japan gained 0.6% to its highest in more than two weeks.


Australian shares rose 0.7%, while South Korea’s benchmark Kospi index was up nearly 1%.


The euro reached its highest level against the dollar since 31 October, up about 0.3% to $ 1.3010.


‘Credibility test’


The breakthrough came after more than 10 hours of talks in Brussels. It was the eurozone’s third meeting in two weeks on Greece.


The deal opens the way for support for Greece’s teetering banks and will allow the government to pay wages and pensions in December.


Continue reading the main story

We simply could not afford to fail”



End Quote Olli Rehn EU economic and monetary affairs comissioner


The leader of the eurozone finance ministers’ group, Jean-Claude Juncker, said Greece would get the next installment of cash on 13 December.


Greece has been waiting since June for the tranche, to help its heavily indebted economy stay afloat.


European Central Bank (ECB) president Mario Draghi said the bailout would “strengthen confidence in Europe and in Greece”.


For his part, Mr Juncker said the deal did not just have financial implications.


“This is not just about money. It is the promise of a better future for the Greek people and for the Euro area as a whole.”


Greece’s international lenders have agreed to take steps to reduce the country’s debts, from an estimated 144%, to 124% of its gross domestic product by 2020.


These include cutting the interest rate on loans to Greece, and returning 11bn euros to Athens in profits from ECB purchases of Greek government bonds.


Ministers have also agreed to help Greece buy back its own bonds from private investors.


So far the ECB, IMF and the European Commission have pledged a total of 240bn euros in rescue loans, of which Greece has received around 150bn euros.


In return, Greece has had to impose several rounds of austerity measures and submit its economy to scrutiny.


The European Union’s commissioner for economic and monetary affairs, Olli Rehn, said it was crucial that a deal had finally been reached.


“For the eurozone this was a real test of our credibility, of our ability to take decisions on the most challenging of issues.


“And it was a test that we simply could not afford to fail.”


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Dog days in Cuba: from shih tzus to schnauzers












HAVANA (AP) — The Cuban capital has played host to political summits and art festivals, ballet tributes and international baseball competitions. Now dog lovers are getting their chance to take center stage.


Hundreds of people from all over Cuba and several other countries came to a scruffy field near Revolution Plaza this past week to preen and fuss over the shih tzus, beagles, schnauzers and cocker spaniels that are the annual Fall Canine Expo’s star attractions. There were even about a dozen bichon habaneros, a mid-sized dog bred on the island since the 17th century.












As dog lovers talked shop, the merely curious strolled the field, checking out the more than 50 breeds on display while carefully dodging the prodigious output of so many dogs.


The four-day competition, which ended Sunday, included competitions in several breeding categories, and judges were flown in from Nicaragua, Colombia and Mexico.


“This is a small, poor country, but Cubans love dogs,” said Miguel Calvo, the president of Cuba’s dog federation, which organized the show. “We make a great effort to breed purebred animals of quality.”


Winners don’t receive any trophy or prize money, but that doesn’t mean the competition is any less fierce.


Anabel Perez, owner of a cocker spaniel named Lisamineli after the U.S. actress, spent more than half an hour coifing the dog’s hair in preparation for the competition, while the owner of a shih tzu named Tiguer meticulously brushed his coat nearby.


“I’m a hairdresser for humans,” explained Tiguer’s owner, Miguel Lopez. “So it’s easy for me. I like shih tzus because they are a lot of work to keep well groomed.”


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Nokia imaging chief to quit












HELSINKI (Reuters) – Nokia‘s long-time imaging chief Damian Dinning has decided to leave the loss-making cellphone maker at the end of this month, the company said in a statement.


The strong imaging capabilities of the new Lumia smartphone models are a key sales argument for the former market leader, which has been burning through cash while losing share in both high-end smartphones and cheaper handsets.












Nokia’s Chief Executive Stephen Elop has replaced most of the top management since he joined in late 2010 and Dinnig is the latest of several executives to leave.


Dinning did not want to move to Finland as part of the phonemakers’ effort to concentrate operations and will join Jaguar Land Rover to head innovations in the field of connected cars, he said on Nokia’s imaging fan site PureViewclub.com.


(Reporting By Tarmo Virki, editing by William Hardy)


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Psoriasis patients look to Hong Kong government for help – and hope












HONG KONG (Reuters) – When Gary Lai first came down with the skin disease psoriasis, he got so tired of the stigma he faced in the outside world that he would lock himself away in his apartment whenever he didn’t have to be at work.


“When you have to apply ointment all over your body, it is impractical. It also has a smell and when you go to work, your colleagues will start asking questions,” said Lai, who was 24 when he was diagnosed.












Now Lai, 41, and other Hong Kong residents suffering from psoriasis – a lifelong autoimmune disease that covers the skin in red, scaly plaques – have joined hands to press the government to help subsidize their high treatment costs.


Affecting up to two percent of the population in Asia, or 125 million people worldwide, this disfiguring disease can take a higher physical and mental toll on patients than cancer and heart disease, past surveys have found.


“During all that time, I experienced great stress and prejudice. In the subway, people around me will stare at me and they think I may infect them,” said Lai, a data analyst. “I can tell from their eyes even if they don’t say anything.”


In psoriasis patients, skin cells grow too fast and rapidly pile up, forming red and inflamed scales or plaques on the skin. While cell reproduction in normal skin takes 28 days, that process in psoriasis patients takes only four days.


The exact cause of psoriasis remains unknown although experts believe it is linked to the immune system where a class of fighter cells attack the body’s own healthy skin cells by mistake. They cite a combination of risk factors, including genetic predisposition and environmental factors.


Dermatologist Yeung Chi-keung said first-line treatments such as creams, exposure to ultraviolet light and oral drugs tend not to work for about 10 percent of patients, who will then require second-line drugs, which are injected.


These injectable drugs now cost an average of HK$ 10,000 (US$ 1,282) a month and getting on Hong Kong‘s general list will mean patients need only pay a nominal administrative fee of $ 10.


“In the last month, we (dermatologists in Hong Kong) proposed to the government to consider subsidizing these drugs,” said Yeung, who is honorary clinical associate professor of dermatology at the University of Hong Kong’s department of medicine.


A spokesman for the Hospital Authority, the body that oversees all public hospitals in Hong Kong, said it would have to make a detailed study before deciding if it will subsidize the treatment of such patients.


“The review process would take into account scientific evidence on safety, efficacy and cost-effectiveness as well as actual clinical experience in the use of drugs. Views of professionals and patient groups will also be considered,” the spokesman added.


For the patients who wait and hope, the stress never goes away.


“When I go to the pool, other swimmers think it is contagious and that I will pollute the water, so they complain to the lifeguard to get rid of me,” Lai said. “We hope the government will put these drugs on their general (subsidized) list.”


(Reporting by Tan Ee Lyn, editing by Elaine Lies)


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Catalan election weakens bid for independence from Spain












BARCELONA, Spain (Reuters) – Separatists in Spain’s Catalonia won regional elections on Sunday but failed to get the resounding mandate they need to push convincingly for a referendum on independence.


Catalan President Artur Mas, who has implemented unpopular spending cuts in an economic crisis, had called an early election to test support for his new drive for independence for Catalonia, a wealthy region in northeastern Spain.












Voters handed almost two thirds of the 135-seat local parliament to four different Catalan separatist parties that all want to hold a referendum on secession from Spain.


But they punished the main separatist group, Mas’s Convergence and Union alliance, or CiU, cutting back its seats to 50 from 62. That will make it difficult for Mas to lead a united drive to hold a referendum in defiance of the constitution and the central government in Madrid.


“Mas clearly made a mistake. He promoted a separatist agenda and the people have told him they want other people to carry out his agenda,” said Jose Ignacio Torreblanca, head of the European Council on Foreign Relations’ Madrid office.


The result will come as a relief for Spanish Prime Minister Mariano Rajoy, who is battling a deep recession and 25 percent unemployment while he struggles to cut high borrowing costs by convincing investors of Spain’s fiscal and political stability.


Mas, surrounded by supporters chanting “independence, independence”, said he would still try to carry out the referendum but added that, “it is more complex, but there is no need to give up on the process.”


Resurgent Catalan separatism had become a major headache for Rajoy, threatening to provoke a constitutional crisis over the legality of a referendum just as he is trying to concentrate on a possible international bailout for troubled Spain.


Frustration over the Spanish tax system, under which Catalonia shares some of its tax revenue with the rest of the country, has revived a long-dormant secessionist spirit in Catalonia. Catalans believe if they could invest more of their taxes at home their economy would prosper.


Mas had tried to ride the separatist wave after hundreds of thousands demonstrated in the streets in September, demanding independence for their region, which has its own language and sees itself as distinct from the rest of Spain.


In a speech to supporters on Sunday night, Mas recognized that he had lost ground and though CiU is still the largest group in Catalan‘s parliament, he said would need the support of another party to govern and to continue pushing through tough economic measures.


“We’ve fallen well short of the majority we had. We’ve been ruling for two years under very tough circumstances,” he said.


Traditional separatists the Republican Left, or ERC, won the second biggest presence in the Catalan parliament, with 21 seats. The Socialists took 20 seats. And Rajoy’s center-right People’s Party won 19.


Three other parties, including two that want a referendum on independence, split the remaining 25 seats. ECFR’s Torreblanca said the Catalan elections were similar to those around Europe in that economic woes have benefited marginal political groups, while larger, traditional parties have lost ground.


MAS MADE BIG BET


Mas’s bet on separatism may have helped out the big winner of Sunday’s election, the Republican Left, which more than doubled its seats in the Catalan parliament to 21 from 10,


“He talked about it so much that he ended up helping the only party that has always been for independence, which is the Republican Left,” said political analyst Ismael Crespo at the Ortega y Gasset research institute.


A legal referendum would require a change to the constitution, and Spain’s main parties in the national parliament, the Socialists and Rajoy’s People’s Party, have shown no appetite for that.


Mas’s CiU had traditionally been a pro-business moderate nationalist party that fought for more autonomy and self-governance for Catalonia without breaking away from Spain.


Mas broke with that tradition in September when he made a big bet on a referendum.


Catalonia, with 7.5 million people, is more populous than Denmark. Its economy is almost as big as Portugal’s and it generates one fifth of Spanish gross domestic product.


After a decade of overspending during Spain’s real estate boom, Catalonia and most of the country’s other regions are struggling to pay state workers and meet debt payments. Unemployment has soared and spending on hospitals and schools has been cut.


Mas was one of the first Spanish leaders to embark on harsh austerity measures after Catalonia’s public deficit soared and the regional government was shunned by debt markets.


Josep Freixas, 37 and unemployed, voted for CiU but recognized the party had lost seats “because people have been really affected by the spending cuts and by the crisis.”


At CiU headquarters on Sunday night Freixas carried a rolled up pro-independence flag – a single star against yellow and red stripes – that has become a symbol of the separatist movement.


Turnout was very high in the election, 68 percent, 10 percentage points higher than in the previous vote two years ago.


Many Catalans are angry that Rajoy has refused to negotiate a new tax deal with their largely self-governing region. Annually, an estimated 16 billion euros ($ 21 billion) in taxes paid in Catalonia, about 8 percent of its economic output, is not returned to the region.


Home to car factories and banks and birthplace of surrealist painter Salvador Dali and architect Antoni Gaudi, the region also has one of the world’s most successful football clubs, FC Barcelona.


Wary that separatism could spread to the Basque Country and beyond, Rajoy said this week that the Catalan election was more important than general elections.


(The story corrects billion to million in 20th paragraph.)


(Editing by Myra MacDonald and Sandra Maler)


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Israel successfully tests missile defense system












JERUSALEM (AP) — Israel successfully tested its newest missile defense system Sunday, the military said, a step toward making the third leg of what Israel calls its “multilayer missile defense” operational.


The “David’s Sling” system is designed to stop mid-range missiles. It successfully passed its test, shooting down its first missile in a drill Sunday in southern Israel, the military said.












The system is designed to intercept projectiles with ranges of up to 300 kilometers (180 miles).


Israel has also deployed Arrow systems for longer-range threats from Iran. The Iron Dome protects against short-range rockets fired by militants in the Gaza Strip and Hezbollah guerrillas in Lebanon. Iron Dome shot down hundreds of rockets from Gaza in this month’s round of fighting.


Israeli Defense Minister Ehud Barak said the success of Iron Dome highlighted the “immense importance” of such systems.


“David’s Sling,” also known “Magic Wand,” is developed by Israel’s Rafael Advanced Defense Systems and U.S.-based Raytheon Co. and is primarily designed to counter the large arsenal of Hezbollah rockets in Lebanon.


The military said the program, which is on schedule for deployment in 2014, would “provide an additional layer of defense against ballistic missiles.”


The next generation of the Arrow, now in the development stage, is set to be deployed in 2016. Called the Arrow 3, it is designed to strike its target outside the atmosphere, intercepting missiles closer to their launch sites. Together, the two Arrow systems would provide two chances to strike down incoming missiles.


Israel also uses U.S.-made Patriot missile defense batteries against mid-range missiles, though these failed to hit any of the 39 Scud missiles fired at Israel from Iraq In the first Gulf War 20 years ago. Manufacturers say the Patriot system has been improved since then.


Middle East News Headlines – Yahoo! News


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15 Cheesy Christmas Music Videos on YouTube












1. “Last Christmas” – Wham!



What would a cheesy Christmas music video roundup be without George Michael — and his mullet, covered by a furry, snow-covered hood? If you like this video, just wait until you see the a cappella Norwegian version.












Click here to view this gallery.


[More from Mashable: 10 Adorable Animals Feeding Other Animals [VIDEOS]]


Now that the turkey has been picked apart and you’ve survived another Black Friday, it is now officially acceptable to listen to Christmas music. If you’ve been secretly listening to “Rudolph the Red-Nosed Reindeer” since early November, crank it up!


One of the best — or worst, depending on your perspective — parts about the holidays is how we embrace corniness. The lyrics are cheesy, the wardrobe is tacky and some traditions are silly.


[More from Mashable: Rebecca Black Shows Off Hidden Talent in New Music Video]


To kick off the season, here are the 15 cheesiest holiday music videos we could find on YouTube. Which is your favorite? Share your pick in the comments below.


Image courtesy of Flickr, ronnie44052


This story originally published on Mashable here.


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“Lincoln” Women: How Sally Field and Gloria Reuben Stole Daniel Day-Lewis’ Show












LOS ANGELES (TheWrap.com) – Steven Spielberg‘s “Lincoln” is, on the face of it, a standard “great man” biopic. Basked in a honeydew light, overflowing with sage advice, Daniel Day-Lewis‘ Great Emancipator is depicted as constantly and self-consciously speaking to the ages well before he belongs to them.


But let us now praise the film’s not-as-famous women. For what rescues “Lincoln” from bombast are the slier and subtler performances by a trio of fantastic and often under-utilized actresses – Sally Field, Gloria Reuben and S. Epatha Merkerson.












Each one uses her limited screen time to etch a devastating portrait of the limitations that faced women in a male-dominated society. After all, if the legislators debating the merits of the 13th Amendment in the movie fret openly that abolishing slavery will begin a slippery slope to black enfranchisement, they seem even more horrified at the prospect that it one day might lead to granting women the right to vote.


Though some critics have griped about Spielberg’s penchant for speechifying in “Lincoln,” there has been near universal praise for Day-Lewis and for Tommy Lee Jones’ work as the wily Thaddeus Stevens. Field’s take on First Lady Mary Todd Lincoln – a woman Louis C.K. quipped on “Saturday Night Live” recently was “historically insane” – has been more divisive.


In TheWrap, for instance, Steve Pond wrote, “Sally Field may well be nominated for Supporting Actress for her Mary Todd Lincoln, but to me her hysteria was one of the least-successful parts of the film.”


Yet Field’s work is in many ways more revelatory than that of Day-Lewis. True, the Irish-Anglo acting god daringly gives the 16th president a historically accurate high voice and indelibly paints a picture of a great orator with an outhouse sense of humor, but his modifications are slight tweaks to the Lincoln myth. Field’s interpretation is a whole-scale reinvention.


Field’s Mary is privately unhinged, true. But she is also a smooth Washington operator, comfortable sparring with Stevens over her White House redecorating and forcibly pressuring her husband to carry the 13th Amendment to the finish line while wielding little more than a fan.


Even her mania is rooted in the death of her young son Willy; an empathetic anchor that keeps Mary from becoming simply the backwoods, social-climbing hysteric she’s been portrayed as in the past.


In screenwriter Tony Kushner, Field finds an eager co-conspirator. As Kushner confessed on NPR, the Lincolns had a turbulent relationship in part because of Abraham Lincoln’s emotional coldness.


“People always think about Mary as being difficult and she absolutely was, but Lincoln wasn’t easy either,” Kushner said. “He was remote and complicated and rather interestingly fond of telling her things that would upset her horribly, like these dreams that he kept having and he would leave her kind of in a state night after night, telling her that he was having these kind of scary dreams.


It’s an enormously complicated relationship and the family is a tragic family.”


The only false note in an otherwise galvanizing portrayal, is having Mary deliver a line that is a too historically self-aware.


“All anyone will remember about me was that I was crazy and ruined your happiness,” Mary says at one point – to which my companion let forth a large guffaw.


Field who packed 25 pounds onto her slender frame and allowed the camera to scan her creased face is a revelation – it’s a reminder that the plucky star of “Norma Rae” is good for more than Boniva ads.


But Mary Todd Lincoln isn’t the only female who elbows her way into this big screen men’s club. Gloria Reuben‘s Elizabeth Keckley is also a marvel.


Dramaturgically it’s a thankless role with Reuben’s freed slave seamstress frequently used as a stand-in for all-antebellum African American suffering. Yet Reuben grounds the performance in a simmering fury and heartbreak, using her eyes to register the peigns of hurt that greets the racist slights Keckley is exposed to on a daily basis.


Her conversation in the White House portico with Daniel Day-Lewis about the meaning of emancipation is a bravura moment – a reminder of just how long a walk to freedom 19th century blacks faced.


Likewise, S. Epatha Merkerson‘s Lydia Smith is perhaps the greatest master class in doing a lot with a little since Judi Dench captured a Best Supporting Actress Oscar in 1998 for her eight-minute cameo in “Shakespeare in Love.”


Smith, the housekeeper and (spoiler alert) common-law wife of Thaddeus Stevens, has two fleeting scenes. In one, she gently removes Jones’ coat as he enters their Washington, D.C., home after the amendment passes, in the other she reads the constitutional addition aloud in bed to her secret-paramour. It is, in the words of another Kushner play, a reminder that “the world only spins forward.”


Indeed, the entire film represents a major step forward for Spielberg whose earlier boy’s adventures were largely all-male affairs. Aside from Embeth Davidtz’s frightened maid in “Schindler’s List,” Whoopi Goldberg’s martyr-like Celie in “The Color Purple” and Karen Allen’s fiery adventurer in “Raiders of the Lost Ark,” the Spielberg women are a weightless bunch. Even great actresses like Julianne Moore in “The Lost World” are given gossamer thin screen time.


Here, transported by Kushner’s words, he allows these women to step forward out of the shadows and into history. Next time maybe he’ll let them take center stage.


Movies News Headlines – Yahoo! News


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